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FR-(alpha) (Y80) pAb

FR-(alpha) (Y80) pAb

Cat no: BS3861

Supplier: Bioworld Technology, Inc.
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The folate receptors consist of five members, (alpha), (beta), (gamma), (gamma)' (which is produced by alternative splicing) and (delta). (beta)-FR is attached to the membrane by a GPI anchor and is expressed in malignant tissues of epithelial and nonepithelial origin. (gamma)-FR is expressed in tissues of hematopoietic origin, such as spleen, thymus and bone marrow. The expression pattern of (delta)-FR is elusive, which suggests that it is highly restricted both spatially and temporally. The (alpha) isoform of the folate receptor is used as a highly selective tumor marker and may be targeted for the delivery of therapeutic compounds to tumor cells by coupling to derivatives of folic acid.
Catalogue number: BS3861
Reactivities: Human, Mouse, Rat
Hosts: Rabbit
Applications: Western Blot
Size: 100ug/100ul
Swiss prot: P15328
Dilutions: WB: 1:500~1:1000
Form: liquid
Storage buffer: 1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2.
Concentration: 1ug/ul
Antigen: Synthetic peptide, corresponding to amino acids 60-110 of Human FR-(alpha).
Species: FR-(alpha) (Y80) pAb detects endogenous levels of FR-(alpha) (Y80) protein.
Molecular weight: ~ 34 kDa
Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage temp: Store at 4 degrees C short term. Aliquot and store at -20 degrees C long term. Avoid freeze-thaw cycles.
Alternative names: FOLR1; FBP; FOLR; FR-ALPHA; MOV18; folate receptor alpha; folate receptors alpha; folr1
Additional info: For research use only, not for use in diagnostic procedure.

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