Frizzled-5/8 (W73) Peptide

Cat no: BS2700P

Supplier: Bioworld Technology, Inc.

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Description
Additional Information

The frizzled gene, originally identified in Drosophila melanogaster, is involved in the development of tissue polarity. The mammalian homolog of frizzled, as well as several secreted mammalian frizzled-related proteins: FRP-1 (also designated SARP2), FRP-2 (also designated SARP1), FRP-3, FRP-4 and SARP3 (also designated FRP-5), have been identified. The frizzled proteins contain seven transmembrane domains, a cysteine-rich domain in the extracellular region and a carboxy terminal Ser/Thr-xxx-Val motif. They function as receptors for Wnt. The frizzled-1 gene maps to human chromosome 7q21 and is expressed in adult heart, placenta, lung, kidney, pancreas, prostate and ovary and in fetal lung and kidney. Frizzled-2 is expressed in adult heart and fetal brain, lung and kidney. The frizzled related proteins FRP-1, FRP-2, FRP-3, FRP-4 and SARP3 are secreted proteins of approximately 30 kDa that contain regions of homology to the cysteine-rich ligand-binding domain of frizzled and a conserved hydrophilic carboxy terminal.

Catalogue number:	BS2700P
Applications:	Block/Neutralize/Inhibit
Swiss prot:	Q9H461/Q13467
Form:	1 mg/ml in DI water.
Purity:	Synthetic peptide Frizzled-5/8 (W73). (Note: the amino acid sequence is proprietary). The purity is > 98%.
Storage temp:	Store at 4 degree C short term. Aliquot and store at -20 degree C long term. Avoid freeze-thaw cycles.
Alternative names:	Fz-5; hFz5; FzE5; FZD5; HFZ5; Fz-8; hFz8; FZD8; FZ-8; hFZ8
Additional info:	This peptide can be used with studies using BS2700 Frizzled-5/8 (W73) pAb.

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Frizzled-5/8 (W73) Peptide

Cat no: BS2700P

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