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Frizzled-6 (G169) Peptide

Frizzled-6 (G169) Peptide

Cat no: BS5721P


Supplier: Bioworld Technology, Inc.
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Frizzled-6 (FZD6, also known as frizzled homolog 6 in Drosophila) is a seven-transmembrane domain receptor that binds the Wnt ligand and influences macroscopic hair patterning and other tissue polarity events. Frizzled-6 protein contains a signal peptide and a cysteine-rich domain (CRD) in the N-terminal extracellular region, and does not contain a C-terminal PDZ domain-binding motif. Frizzled-3 and frizzled-6 influence neural tube closure and the planar orientation of hair bundles on a subset of auditory and vestibular sensory cells. Madin-Darby canine kidney (MDCK) cells are competent to form tubules in vitro and express the frizzled-6 receptor, which is known to form a complex with Wnt-4 through the CRD in this cell type. Frizzled-6 is expressed as a 4.4 kb mRNA in various human tissues, including adult heart, brain, placenta, lung, liver, skeletal muscle, kidney, pancreas, thymus, prostate, testis, ovary, small intestine and colon.
Catalogue number: BS5721P
Applications: Block/Neutralize/Inhibit
Swiss prot: O60353
Form: 1 mg/ml in DI water.
Purity: Synthetic peptide Frizzled-6 (G169). (Note: the amino acid sequence is proprietary). The purity is > 98%.
Storage temp: Store at 4 degree C short term. Aliquot and store at -20 degree C long term. Avoid freeze-thaw cycles.
Alternative names: Frizzled6; Frizzled 6; Fz-6; hFz6; FZD6; FZD-6
Additional info: This peptide can be used with studies using BS5721 Frizzled-6 (G169) pAb.

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