Frizzled-7 (Y87) Peptide

Cat no: BS2774P

Supplier: Bioworld Technology, Inc.

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The frizzled gene, originally identified in Drosophila melanogaster, is involved in the development of tissue polarity. The mammalian homolog of frizzled, as well as several secreted mammalian frizzled-related proteins: FRP-1 (also designated SARP2), FRP-2 (also designated SARP1), FRP-3, FRP-4 and SARP3 (also designated FRP-5), have been identified. The frizzled proteins contain seven transmembrane domains, a cysteine-rich domain in the extracellular region and a carboxy terminal Ser/Thr-xxx-Val motif. They function as receptors for Wnt. frizzled-7 has a Lys-Thr-X-X-X-Trp motif which is involved in the activation of the Wnt/beta-catenin signaling pathway. frizzled-7 is an integral membrane protein showing a high expression in adult skeletal muscle, fetal kidney, fetal lung, adult heart, brain and placenta. It is specifically expressed in squamous cell esophageal carcinomas.

Catalogue number:	BS2774P
Applications:	Block/Neutralize/Inhibit
Swiss prot:	O75084
Form:	1 mg/ml in DI water.
Purity:	Synthetic peptide Frizzled-7 (Y87). (Note: the amino acid sequence is proprietary). The purity is > 98%.
Storage temp:	Store at 4 degree C short term. Aliquot and store at -20 degree C long term. Avoid freeze-thaw cycles.
Alternative names:	Frizzled7; Frizzled 7; Fz-7; hFz7; FzE3; FZD7
Additional info:	This peptide can be used with studies using BS2774 Frizzled-7 (Y87) pAb.

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Frizzled-7 (Y87) Peptide

Cat no: BS2774P

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