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FSHR (R247) Peptide

FSHR (R247) Peptide

Cat no: BS2618P

Supplier: Bioworld Technology, Inc.
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Follicle-stimulating hormone receptor (FSHR) is a 695 amino acid G-protein coupled receptor. FSH binds to the receptor in a hand-clasp fashion via its alpha and beta subunits. While the alpha subunit of FSH is involved in the binding of FSH to the receptor, the beta subunit stabilizes this interaction. Linkage studies suggest that a missense mutation in the FSHR gene can cause reduced FSH binding affinity and lead to a condition known as hypergonadotropic ovarian dysgenesis (ODG). In males however, this mutation does not appear to have a detrimental affect on fertility. It is believed that a mutation in the FSHR gene is also associated with ovarian hyperstimulation syndrome; a condition characterized by the presence of multiple serous and hemorrhagic follicular cysts lined by luteinized cells.
Catalogue number: BS2618P
Applications: Block/Neutralize/Inhibit
Swiss prot: P23945
Form: 1 mg/ml in DI water.
Purity: Synthetic peptide FSHR (R247). (Note: the amino acid sequence is proprietary). The purity is > 98%.
Storage temp: Store at 4 degree C short term. Aliquot and store at -20 degree C long term. Avoid freeze-thaw cycles.
Alternative names: Follicle-stimulating hormone receptor; FSH-R; Follitropin receptor; LGR1
Additional info: This peptide can be used with studies using BS2618 FSHR (R247) pAb.

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