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FucT-IV (E71) pAb

FucT-IV (E71) pAb

Cat no: BS3444

Supplier: Bioworld Technology, Inc.
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FucT-IV ((alpha) 1,3-fucosyltransferase IV), also known as FUT4, FCT3A or ELFT, is a 405 amino acid single-pass type II membrane protein that localizes to Golgi stacks. During embryogenesis, FucT-IV is highly expressed in skin, liver, kidney, muscle and small intestine where it functions to catalyze the glycosidic attachment of (alpha)-fucose to various molecules, such as N-acetyllactosamines. Via its catalytic activity, FucT-IV participates in the synthesis of carbohydrate molecules like the cell-adhesion antigen CD15 (also known as Lewis X), thereby playing a roll in cell cycle events such as apoptosis and cellcell binding. Overexpression of FucT-IV is implicated in epithelial cancers, suggesting a possible role for FucT-IV in carcinogenesis.
Catalogue number: BS3444
Reactivities: Human
Hosts: Rabbit
Applications: Immunohistochemistry
Size: 100ug/100ul
Swiss prot: P22083
Dilutions: IHC: 1:50~1:200
Form: liquid
Storage buffer: 1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2.
Concentration: 1ug/ul
Antigen: Synthetic peptide, corresponding to amino acids 45-90 of Human FucT-IV.
Species: FucT-IV (E71) pAb detects endogenous levels of FucT-IV protein.
Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage temp: Store at 4 degrees C short term. Aliquot and store at -20 degrees C long term. Avoid freeze-thaw cycles.
Alternative names: Alpha-(1; 3)-fucosyltransferase; EC=2.4.1.-; ELAM-1 ligand fucosyltransferase; Fucosyltransferase 4; Fucosyltransferase IV; Fuc-TIV; FucT-IV; Galactoside 3-L-fucosyltransferase; ELFT; FCT3A; FUT4
Additional info: For research use only, not for use in diagnostic procedure.

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