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GABAA R(delta) (D181) pAb

GABAA R(delta) (D181) pAb

Cat no: BS3863

Supplier: Bioworld Technology, Inc.
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GAD-65 and GAD-67, glutamate decarboxylases, function to catalyze the production of GABA (gamma-aminobutyric acid). In the central nervous system GABA functions as the main inhibitory transmitter by increasing a Cl- conductance that inhibits neuronal firing. GABA has been shown to activate both ionotropic (GABAA) and metabotropic (GABAB) receptors as well as a third class of receptors called GABAC. Both GABAA and GABAC are ligand-gated ion channels, however, they are structurally and functionally distinct. Members of the GABAA receptor family include GABAA R(alpha)1-6, GABAA R (beta)1-3, GABAA R(gamma)1-3, GABAA R(delta), GABAA RE, GABAA R?1 and GABAA R?2. The GABAB family is composed of GABAB R1(alpha) and GABAB R1(beta). GABA transporters have also been identified and include GABA T-1, GABA T-2 and GABA T-3 (also designated GAT-1, -2, and -3). The GABA transporters function to terminate GABA action.
Catalogue number: BS3863
Reactivities: Human, Mouse, Rat
Hosts: Rabbit
Applications: Western Blot
Size: 100ug/100ul
Swiss prot: O14764
Dilutions: WB: 1:500~1:1000
Form: liquid
Storage buffer: 1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2.
Concentration: 1ug/ul
Antigen: Synthetic peptide, corresponding to amino acids 151-200 of Human GABAA R(delta).
Species: GABAA R(delta) (D181) pAb detects endogenous levels of GABAA R(delta) protein.
Molecular weight: ~ 51 kDa
Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage temp: Store at 4 degrees C short term. Aliquot and store at -20 degrees C long term. Avoid freeze-thaw cycles.
Alternative names: Gamma-aminobutyric acid receptor subunit delta; GABA(A) receptor subunit delta; GABRD; GABAA R(delta)
Additional info: For research use only, not for use in diagnostic procedure.

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