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GABAA Rbeta2 (R431) Peptide

Cat no: BS2907P

GABAA Rbeta2 (R431) Peptide

GAD-65 and GAD-67, glutamate decarboxylases, function to catalyze the production of GABA (gamma-aminobutyric acid). In the central nervous system GABA functions as the main inhibitory transmitter by increasing a Cl- conductance that inhibits neuronal firing. GABA has been shown to activate both ionotropic (GABAA) and metabotropic (GABAB) receptors as well as a third class of receptors called GABAC. Both GABAA and GABAC are ligand-gated ion channels, however, they are structurally and functionally distinct. Members of the GABAA receptor family include GABAA Ralpha1-6, GABAA R beta1-3, GABAA Rgamma 1-3, GABAA Rdelta, GABAA RE, GABAA R?1 and GABAA R?2. The GABAB family is composed of GABAB R1alpha and GABAB R1beta. GABA transporters have also been identified and include GABA T-1, GABA T-2 and GABA T-3 (also designated GAT-1, -2, and -3). The GABA transporters function to terminate GABA action.

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SPECIFICATIONS

Catalog Number

BS2907P

Applications

BNI

Form

1 mg/ml in DI water.

Purity

Synthetic peptide GABAA Rbeta2 (R431). (Note: the amino acid sequence is proprietary). The purity is > 98%.

Swiss Prot

P47870

Storage Temp

Store at 4 degree C short term. Aliquot and store at -20 degree C long term. Avoid freeze-thaw cycles.

Additional Info

This peptide can be used with studies using BS2907 GABAA Rbeta2 (R431) pAb.

Alternative Names

Gamma-aminobutyric acid receptor subunit beta-2; GABA(A) receptor subunit beta-2; GABRB2; GABAARbeta2

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