GAD-67 (A492) Peptide

Cat no: BS1135P

Supplier: Bioworld Technology, Inc.

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Description
Additional Information

GAD-65 and GAD-67 are members of the group II decarboxylase family of proteins and are responsible for catalyzing the rate limiting step in the production of GABA (gamma -aminobutyric acid) from L-glutamic acid. Although both GADs are found in the brain, GAD-65 localizes to synaptic vesicle membranes in nerve terminals, while GAD-67 is distributed throughout the cell. GAD-67 is responsible for the basal levels of GABA synthesis. In the case of a heightened demand for GABA in neurotransmission, GAD-65 will transiently activate to assist in GABA production. The loss of GAD-65 is detrimental and can impair GABA neurotransmission, however the loss of GAD-67 is lethal. Due to alternative splicing, two isoforms exist for GAD-67: the predominant GAD-67 form and the minor GAD-25 form.

Catalogue number:	BS1135P
Applications:	Block/Neutralize/Inhibit
Swiss prot:	Q99259
Form:	1 mg/ml in DI water.
Purity:	Synthetic peptide GAD-67 (A492). (Note: the amino acid sequence is proprietary). The purity is > 98%.
Storage temp:	Store at 4 degree C short term. Aliquot and store at -20 degree C long term. Avoid freeze-thaw cycles.
Alternative names:	Glutamate decarboxylase 1; 67 kDa glutamic acid decarboxylase; GAD 67; Glutamate decarboxylase 67 kDa isoform; GAD1; GAD; GAD67; GAD-1; GAD 1
Additional info:	This peptide can be used with studies using BS1135 GAD-67 (A492) pAb.

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GAD-67 (A492) Peptide

Cat no: BS1135P

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