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Galectin-4 (K83) Peptide

Cat no: BS2529P

Galectin-4 (K83) Peptide

Galectins are a family of soluble beta-galactoside-binding animal lectins that modulate cell-to-cell adhesion and cell-to-extracellular matrix (ECM) interactions and play a role in tumor progression, pre-mRNA splicing and apoptosis. One member of this family, Galectin-4, also known as Gal-4, L36 or LGALS4 maps to human chromosome 19q13.13 and encodes a 36-37 kDa protein. The Galectin-4 protein is composed of 323 amino acids and contains two homologous carbohydrate recognition domains (CRD) and all amino acids typically conserved in the galectin family. Expression of Galectin-4 correlates with the malignant potential of human hepatocellular carcinoma (HCC) and is differentially regulated depending on cell-cell contact, serum growth factors, cell growth and cell differentiation status. Galectin-4 expression is detected in epithelial cells of the colon, rectum, intestine, and in HT29 and LS174T cell lines. Galectin-4 is underexpressed in colorectal cancer and is preferentially upregulated in cells prone to peritoneal dissemination.

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SPECIFICATIONS

Catalog Number

BS2529P

Applications

BNI

Form

1 mg/ml in DI water.

Purity

Synthetic peptide Galectin-4 (K83). (Note: the amino acid sequence is proprietary). The purity is > 98%.

Swiss Prot

P56470

Storage Temp

Store at 4 degree C short term. Aliquot and store at -20 degree C long term. Avoid freeze-thaw cycles.

Additional Info

This peptide can be used with studies using BS2529 Galectin-4 (K83) pAb.

Alternative Names

LGALS4; GAL4; GALECTIN-4; L36LBP

SUPPLIER INFO

Bioworld Technology, Inc.

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