GBP1 (E99) Peptide

Cat no: BS3028P

Supplier: Bioworld Technology, Inc.

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GBP1 (guanylate binding protein 1) is a 592 amino acid protein member of the GTPase protein family and is able to bind specifically to guanine nucleotides such as GMP, GDP and GTP. GMP is hydrolyzed to GTP in two consecutive cleavage step, both of which are carried out by GBP1. Localized to the cytoplasm, GBP1 is expressed in endothelial cells of the vascular system and is induced by IFN-gamma during macrophage induction. GBP1 is thought to regulate the expression of MMP-1, which mediates the proliferation and invasiveness of endothelial cells. GBP1 plays a key role in regulating inflammatory cytokines and provides protection against vesicular stomatitis and encephalomyocarditis viruses. GBP1 expression is highly induced in the vessels of skin diseases such as psoriasis and Kaposi

Catalogue number:	BS3028P
Applications:	Block/Neutralize/Inhibit
Swiss prot:	P32455
Form:	1 mg/ml in DI water.
Purity:	Synthetic peptide GBP1 (E99). (Note: the amino acid sequence is proprietary). The purity is > 98%.
Storage temp:	Store at 4 degree C short term. Aliquot and store at -20 degree C long term. Avoid freeze-thaw cycles.
Alternative names:	Interferon-induced guanylate-binding protein 1; GTP-binding protein 1; GBP-1; HuGBP-1; Guanine nucleotide-binding protein 1; GBP1
Additional info:	This peptide can be used with studies using BS3028 GBP1 (E99) pAb.

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GBP1 (E99) Peptide

Cat no: BS3028P

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