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GBP1 (E99) Peptide

Cat no: BS3028P

GBP1 (E99) Peptide

GBP1 (guanylate binding protein 1) is a 592 amino acid protein member of the GTPase protein family and is able to bind specifically to guanine nucleotides such as GMP, GDP and GTP. GMP is hydrolyzed to GTP in two consecutive cleavage step, both of which are carried out by GBP1. Localized to the cytoplasm, GBP1 is expressed in endothelial cells of the vascular system and is induced by IFN-gamma during macrophage induction. GBP1 is thought to regulate the expression of MMP-1, which mediates the proliferation and invasiveness of endothelial cells. GBP1 plays a key role in regulating inflammatory cytokines and provides protection against vesicular stomatitis and encephalomyocarditis viruses. GBP1 expression is highly induced in the vessels of skin diseases such as psoriasis and Kaposi

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SPECIFICATIONS

Catalog Number

BS3028P

Applications

BNI

Form

1 mg/ml in DI water.

Purity

Synthetic peptide GBP1 (E99). (Note: the amino acid sequence is proprietary). The purity is > 98%.

Swiss Prot

P32455

Storage Temp

Store at 4 degree C short term. Aliquot and store at -20 degree C long term. Avoid freeze-thaw cycles.

Additional Info

This peptide can be used with studies using BS3028 GBP1 (E99) pAb.

Alternative Names

Interferon-induced guanylate-binding protein 1; GTP-binding protein 1; GBP-1; HuGBP-1; Guanine nucleotide-binding protein 1; GBP1

SUPPLIER INFO

Bioworld Technology, Inc.

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