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GCP5 (I779) pAb

GCP5 (I779) pAb

Cat no: BS3303

Supplier: Bioworld Technology, Inc.
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The (gamma)-Tubulin complex is composed of (gamma) Tubulin and the (gamma)-Tubulin complexassociated proteins GCP2, GCP3, GCP4, GCP5 and GCP6, all of which are essential components of microtubule organizing centers. (gamma)-Tubulin complex components are localized to both the centrosome, where they are involved in microtubule nucleation, and to the cytoplasm, where they exist as soluble complexes that can be recruited to the centrosome as needed. Although the GCP proteins are related, they have distinct roles which contribute to the proper function of the (gamma)-Tubulin complex. GCP5 ((gamma)-Tubulin complex component 5), also known as TUBGCP5, is a 1,024 amino acid member of the (gamma)-Tubulin complex and is highly expressed in heart and skeletal muscle. Defects in the gene encoding GCP5 are implicated in Prader-Willi syndrome (PWS), a rare genetic disorder associated with obesity, compulsive behavior and lower intellectual ability.
Catalogue number: BS3303
Reactivities: Human, Mouse
Hosts: Rabbit
Applications: Immunohistochemistry, Western Blot
Size: 100ug/100ul
Swiss prot: Q96RT8
Dilutions: WB: 1:500~1:1000 IHC: 1:50~1:200
Form: liquid
Storage buffer: 1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2.
Concentration: 1ug/ul
Antigen: Synthetic peptide, corresponding to amino acids 746-794 of Human GCP5.
Species: GCP5 (I779) pAb detects endogenous levels of GCP5 protein.
Molecular weight: ~ 118 kDa
Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage temp: Store at 4 degrees C short term. Aliquot and store at -20 degrees C long term. Avoid freeze-thaw cycles.
Alternative names: TUBGCP5
Additional info: For research use only, not for use in diagnostic procedure.

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