Ghrelin pAb

Small synthetic molecules called growth-hormone secretagogues (GHSs) act through GSH-R to stimulate the release of GH from the pituitary. Ghrelin is an endogenous levels of ligand for the growth hormone secretagogue receptor (GHS-R). Ghrelin and GHRH are involved in the regulation of GH release from the pituitary. GHRH exerts its action through high-affinity GHRH receptors (GHRH-R) present in the anterior pituitary. The acylated peptide of ghrelin specifically releases GH both in vivo and in vitro and is found in stomach tissue. GH plays a crucial role in stimulating and controlling the growth, metabolism and differentiation of many mammalian cell types by modulating the synthesis of multiple mRNA species. The gene encoding ghrelin maps to human chromosome 3p26-p25.

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SPECIFICATIONS

Catalog Number

BS6800

Size

100ug/100ul

Applications

IHC, WB

Hosts

Rabbit

Reactivities

Hum, Mouse, Rat

Form

liquid

Purity

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Antigen

Recombinant full length Human Ghrelin.

Species

Ghrelin pAb detects endogenous levels of Ghrelin protein.

Dilutions

WB: 1:500~1:2000\nIHC: 1:50~1:200

Swiss Prot

Q9UBU3

Storage Temp

Store at 4 degrees C short term. Aliquot and store at -20 degrees C long term. Avoid freeze-thaw cycles.

Concentration

1ug/ul

Storage Buffer

1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2.

Additional Info

For research use only, not for use in diagnostic procedure.

Molecular Weight

~ 13 kDa

Alternative Names

Appetite regulating hormone; Ghrelin 27; Ghrelin 28; Ghrelin; Ghrelin/obestatin prepropeptide; ghrl; GHRL; Growth hormone releasing peptide; Growth hormone secretagogue; Growth hormone-releasing peptide; M46 protein; Motilin related peptide; Motilin-related peptide; MTLRP; Obestatin; Protein M46;