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Glut 4 (R271) Peptide

Cat no: BS3680P

Glut 4 (R271) Peptide

Glut4. In response to insulin, Glut4 is quickly shuttled from an intracellular storage site to the plasma membrane, where it binds glucose. In contrast, the ubiquitously expressed glucose transporter Glut1 is constitutively targeted to the plasma membrane and shows a much less dramatic translocation in response to insulin. Glut1 and Glut4 are twelve pass transmembrane proteins (12TM) whose carboxy-termini may dictate their cellular localization. Aberrant Glut4 expression has been suggested to contribute to such maladies as obesity and diabetes. Glut4 null mice have shown that while functional Glut4 protein is not required for maintaining normal glucose levels, it is necessary for sustained growth, normal cellular glucose, fat metabolism and prolonged longevity.

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SPECIFICATIONS

Catalog Number

BS3680P

Applications

BNI

Form

1 mg/ml in DI water.

Purity

Synthetic peptide Glut 4 (R271). (Note: the amino acid sequence is proprietary). The purity is > 98%.

Swiss Prot

P14672

Storage Temp

Store at 4 degree C short term. Aliquot and store at -20 degree C long term. Avoid freeze-thaw cycles.

Additional Info

This peptide can be used with studies using BS3680 Glut 4 (R271) pAb.

Alternative Names

Solute carrier family 2; facilitated glucose transporter member 4; Glucose transporter type 4; insulin-responsive; GLUT-4; GLUT4; SLC2A4

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