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GNAI1 pAb

GNAI1 pAb

Cat no: BS60415

Supplier: Bioworld Technology, Inc.
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Heterotrimeric G proteins function to relay information from cell surface receptors to intracellular effectors. Each of a very broad range of receptors specifically detects an extracellular stimulus (a photon, pheromone, odorant, hormone or neurotransmitter) while the effectors (i.e. adenyl cyclase), which act to generate one or more intracellular messengers, are less numerous. In mammals, G protein (alpha), (beta) and (gamma) polypeptides are encoded by at least 16, 4 and 7 genes, respectively. Most interest in G proteins has been focused on their (alpha) subunits, since these proteins bind and hydrolyze GTP and most obviously regulate the activity of the best studied effectors. Four distinct classes of G(alpha) subunits have been identified; these include Gs, Gi, Gq and G(alpha) 12/13. The Gi class comprises all the known (alpha) subunits that are susceptible to pertussis toxin modifications, including G(alpha) i-1, G(alpha) i-2, G(alpha) i-3, G(alpha) o, G(alpha) t1, G(alpha) t2, G(alpha) z and G(alpha) gust. Of these, the three G(alpha) i subtypes function to open atrial potassium channels.
Catalogue number: BS60415
Reactivities: Human, Mouse, Rat
Hosts: Rabbit
Applications: Western Blot
Size: 100ug/100ul
Swiss prot: P63096
Dilutions: WB: 1:500~1:1000
Form: liquid
Storage buffer: 1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2.
Concentration: 1ug/ul
Antigen: A synthetic peptide corresponding to residues in Human GNAI1.
Species: GNAI1 pAb detects endogenous levels of GNAI1 protein.
Molecular weight: ~ 45 kDa
Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage temp: Store at 4 degrees C short term. Aliquot and store at -20 degrees C long term. Avoid freeze-thaw cycles.
Alternative names: Guanine nucleotide-binding protein G(i) subunit alpha-1; Adenylate cyclase-inhibiting G alpha protein; G(alpha) i-1
Additional info: For research use only, not for use in diagnostic procedure.

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