GNPAT (F365) pAb

GNPAT is a key enzyme located in the peroxisomal membrane which is essential to the synthesis of ether phospholipids. Mutations in GNPAT are associated with rhizomelic chondrodysplasia punctata type 2, which is characterized by rhizomelic shortening of femur and humerus, vertebral disorders, cataract, cutaneous lesions and severe mental retardation.

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SPECIFICATIONS

Catalog Number

BS3110

Size

100ug/100ul

Applications

IHC, WB

Hosts

Rabbit

Reactivities

Hum

Form

liquid

Purity

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Antigen

Synthetic peptide, corresponding to amino acids 341-390 of Human GNPAT.

Species

GNPAT (F365) pAb detects endogenous levels of GNPAT protein.

Dilutions

WB: 1:500~1:1000\r\nIHC: 1:50~1:200

Swiss Prot

O15228

Storage Temp

Store at 4 degrees C short term. Aliquot and store at -20 degrees C long term. Avoid freeze-thaw cycles.

Concentration

1ug/ul

Storage Buffer

1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2.

Additional Info

For research use only, not for use in diagnostic procedure.

Molecular Weight

~ 77 kDa

Alternative Names

DHAPAT; DAPAT; DAP AT; Glyceronephosphate O acyltransferase; Dihydroxyacetone phosphate acyltransferase; Acyl CoA dihydroxyacetonephosphateacyltransferase; DHAP AT; OTTHUMP00000036147; EC 2.3.1.42