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GnT(alpha)4 (H65) pAb

GnT(alpha)4 (H65) pAb

Cat no: BS3069

Supplier: Bioworld Technology, Inc.
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Alpha 1,4-N-acetylflucosaminyltransferase ((alpha)4Gn-T) mediates the biosynthesis of mucin type glycoprotein (O-glycan). (alpha)4Gn-T acts as the key enzyme for the formation of the unique glycan GlcNAc(alpha)1-4Gal(beta)1-R, and most efficiently transfers N-acetylglucosamine (GlcNAc) to core 2 branched O-glycans. (alpha)4Gn-T is a single-pass type II membrane protein associated with the Golgi apparatus and contains the conserved DXD motif involved in catalytic activity. It is expressed in stomach and pancreas, as well as in gastric cancer cells. (alpha)4Gn-T is not expressed in peripheral blood cells, making it a useful biomarker for pancreatic cancer. (alpha)4Gn-T and Mucin 6 expression is upregulated in the gastric mucosa of H. pylori infected patients, which suggest the involvement of (alpha)4Gn-T in defense against H. pylori infection.
Catalogue number: BS3069
Reactivities: Human, Mouse, Rat
Hosts: Rabbit
Applications: Western Blot
Size: 100ug/100ul
Swiss prot: Q9UNA3
Dilutions: WB: 1:500~1:1000
Form: liquid
Storage buffer: 1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2.
Concentration: 1ug/ul
Antigen: Synthetic peptide, corresponding to amino acids 32-82 of Human GnT(alpha)4.
Species: GnT(alpha)4 (H65) pAb detects endogenous levels of (alpha)-1,4-N-acetylglucosaminyltransferase protein.
Molecular weight: ~ 39 kDa
Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage temp: Store at 4 degrees C short term. Aliquot and store at -20 degrees C long term. Avoid freeze-thaw cycles.
Alternative names: Alpha-1;4-N-acetylglucosaminyltransferase; (alpha)4GnT; A4GNT; GnT(alpha)4; (alpha)4 GnT
Additional info: For research use only, not for use in diagnostic procedure.

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