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GnTalpha4 (H65) Peptide

GnTalpha4 (H65) Peptide

Cat no: BS3069P


Supplier: Bioworld Technology, Inc.
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Alpha 1,4-N-acetylflucosaminyltransferase (alpha4Gn-T) mediates the biosynthesis of mucin type glycoprotein (O-glycan). alpha4Gn-T acts as the key enzyme for the formation of the unique glycan GlcNAcalpha1-4Galbeta1-R, and most efficiently transfers N-acetylglucosamine (GlcNAc) to core 2 branched O-glycans. alpha4Gn-T is a single-pass type II membrane protein associated with the Golgi apparatus and contains the conserved DXD motif involved in catalytic activity. It is expressed in stomach and pancreas, as well as in gastric cancer cells. alpha4Gn-T is not expressed in peripheral blood cells, making it a useful biomarker for pancreatic cancer. alpha4Gn-T and Mucin 6 expression is upregulated in the gastric mucosa of H. pylori infected patients, which suggest the involvement of alpha4Gn-T in defense against H. pylori infection.
Catalogue number: BS3069P
Applications: Block/Neutralize/Inhibit
Swiss prot: Q9UNA3
Form: 1 mg/ml in DI water.
Purity: Synthetic peptide GnTalpha4 (H65). (Note: the amino acid sequence is proprietary). The purity is > 98%.
Storage temp: Store at 4 degree C short term. Aliquot and store at -20 degree C long term. Avoid freeze-thaw cycles.
Alternative names: Alpha-1;4-N-acetylglucosaminyltransferase; alpha4GnT; A4GNT; GnTalpha4; alpha4 GnT
Additional info: This peptide can be used with studies using BS3069 GnTalpha4 (H65) pAb.

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