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GPR120 (V259) pAb

GPR120 (V259) pAb

Cat no: BS2778

Supplier: Bioworld Technology, Inc.
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GPR120, a member of the rhodopsin family of G protein-coupled receptors (GPCRs), is a 377 amino acid protein which is expressed in the intestine. GPR120 is a receptor for unsaturated long-chain FFAs (free fatty acids). FFAs act as signaling molecules and are an important energy source. They also employ various physiological responses through their GPCRs. One such response occurs when dietary FFAs stimulate GPR120. This stimulation promotes the secretion of Glucagon-like peptide-1 (GLP-1) in vivo and in vitro.GLP-1 belongs to the class of molecules known as the incretins, which are associated with insulin secreted from the pancreas as a result of food intake.GLP-1 also inhibits Glucagon and gastric acid secretion and gastric emptying. Consequently, the role of GPR120 in the secretion of GLP-1 is critical in the treatment of diabetes.
Catalogue number: BS2778
Reactivities: Human, Mouse, Rat
Hosts: Rabbit
Applications: Immunofluorescence, Western Blot
Size: 100ug/100ul
Swiss prot: Q5NUL3
Dilutions: WB: 1:500~1:1000 IF: 1:50~1:200
Form: liquid
Storage buffer: 1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2.
Concentration: 1ug/ul
Antigen: Synthetic peptide, corresponding to amino acids 226-284 of Human GPR120.
Species: GPR120 (V259) pAb detects endogenous levels of GPR120 protein.
Molecular weight: ~ 38 kDa
Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage temp: Store at 4 degrees C short term. Aliquot and store at -20 degrees C long term. Avoid freeze-thaw cycles.
Alternative names: G-protein coupled receptor PGR4; G-protein coupled receptor GT01; G-protein coupled receptor 129; GPR120; GPR129; PGR4; GT01
Additional info: For research use only, not for use in diagnostic procedure.

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