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GPR176 pAb

GPR176 pAb

Cat no: BS5743

Supplier: Bioworld Technology, Inc.
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G protein-coupled receptors (GPRs), also known as seven transmembrane receptors, heptahelical receptors or 7TM receptors, comprise a superfamily of proteins that play a role in many different stimulus-response pathways. G protein coupled receptors translate extracellular signals into intracellular signals (G protein activation) and they respond to a variety of signaling molecules, such as hormones and neurotransmitters. GPR176 (G protein-coupled receptor 176), also known as HB-954, GPR or Gm1012, is a 515 amino acid multi-pass membrane protein belonging to the G-protein coupled receptor 1 family. Expressed in brain and spleen, with trace expression in kidney, GPR176 functions as an orphan receptor that is thought to play a role in signaling events throughout the cell. Containing four N-glycosylation sites, seven transmembrane domains and a large C-terminal cytosolic domain, GPR176 is encoded by a gene mapping to human chromosome 15q14.
Catalogue number: BS5743
Reactivities: Human, Mouse, Rat
Hosts: Rabbit
Applications: Immunofluorescence, Western Blot
Size: 100ug/100ul
Swiss prot: Q14439
Dilutions: WB: 1:500~1:1000 IF: 1:50~1:200
Form: liquid
Storage buffer: 1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2.
Concentration: 1ug/ul
Antigen: Synthetic peptide, corresponding to amino acids 470-515 of Human GPR176.
Species: GPR176 pAb detects endogenous levels of GPR176 protein.
Molecular weight: ~ 57 kDa
Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage temp: Store at 4 degrees C short term. Aliquot and store at -20 degrees C long term. Avoid freeze-thaw cycles.
Alternative names: Probable G-protein coupled receptor 176; HB-954; HB954
Additional info: For research use only, not for use in diagnostic procedure.

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