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GPR75 pAb

GPR75 pAb

Cat no: BS5752

Supplier: Bioworld Technology, Inc.
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G protein-coupled receptors (GPRs), also known as seven transmembrane receptors, heptahelical receptors or 7TM receptors, comprise a superfamily of proteins that play a role in many different stimulus-response pathways. G protein coupled receptors translate extracellular signals into intracellular signals (G protein activation) and they respond to a variety of signaling molecules, such as hormones and neurotransmitters. GPR75 is a 540 amino acid multi-pass membrane protein that functions as an orphan receptor and belongs to the GPR1 family. Highly expressed in spinal cord and brain, GPR75 is also found at low levels in retinal pigment epithelium. The gene encoding GPR75 maps to human chromosome 2, which consists of 237 million bases, encodes over 1,400 genes and makes up approximately 8% of the human genome. A number of genetic diseases are linked to genes on chromosome 2 including Harlequin icthyosis, sitosterolemia and Alstr
Catalogue number: BS5752
Reactivities: Human, Mouse, Rat
Hosts: Rabbit
Applications: Western Blot
Size: 100ug/100ul
Swiss prot: O95800
Dilutions: WB: 1:500~1:1000 ICC: 1:50~1:200
Form: liquid
Storage buffer: 1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2.
Concentration: 1ug/ul
Antigen: Synthetic peptide, corresponding to amino acids 423-468 of Human GPR75.
Species: GPR75 pAb detects endogenous levels of GPR75 protein.
Molecular weight: ~ 59 kDa
Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage temp: Store at 4 degrees C short term. Aliquot and store at -20 degrees C long term. Avoid freeze-thaw cycles.
Alternative names: Probable G-protein coupled receptor 75
Additional info: For research use only, not for use in diagnostic procedure.

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