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GPR91 (A135) Peptide

GPR91 (A135) Peptide

Cat no: BS2961P

Supplier: Bioworld Technology, Inc.
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GPR91 (formerly known as P2U2) is a G protein-coupled, dicarboxylic acid succinate receptor. It has a high level of expression in the kidney, predominantly in the proximal tubules, and localizes to the plasma membrane. It has also been found at low levels in the liver and the spleen. GPR91 functions as a citric acid cycle intermediate succinate receptor. Two signaling pathways result from GPR91 activation, the pertussis-toxin-sensitive Gi/Go pathway and the pertussis-toxin-insensitive Gq pathway. Four amino acid residues are necessary for GPR91 activation by succinate: Arg 99, His 103, Arg 252 and Arg 281. GPR91 plays an important role in the succinate-induced hypertensive effect and may be involved in renovascular hypertension, a disease linked to diabetes, renal failure and atherosclerosis.
Catalogue number: BS2961P
Applications: Block/Neutralize/Inhibit
Swiss prot: Q9BXA5
Form: 1 mg/ml in DI water.
Purity: Synthetic peptide GPR91 (A135). (Note: the amino acid sequence is proprietary). The purity is > 98%.
Storage temp: Store at 4 degree C short term. Aliquot and store at -20 degree C long term. Avoid freeze-thaw cycles.
Alternative names: G-protein coupled receptor 91; P2Y purinoceptor 1-like; SUCNR1; GPR91
Additional info: This peptide can be used with studies using BS2961 GPR91 (A135) pAb.

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