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Granzyme K (H85) Peptide

Granzyme K (H85) Peptide

Cat no: BS2413P

Supplier: Bioworld Technology, Inc.
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The granzyme family of proteins belong to the larger peptidase S1 family. Granzyme A and granzyme B are serine proteases that facilitate apoptotic signaling in cytotoxic T lymphocytes (CTL) and natural killer (NK) cells. Within the granules of activated CTLs, granzyme A and B are processed and converted to their active forms by the lysosomal cysteine protease cathepsin C. Once cleaved, these active proteases target distinct substrates for proteolysis and, thereby, mediate apoptosis through two different pathways. Granzyme H localizes to cytoplasmic granules of cytolytic T lymphocytes and is important for target cell lysis in cell-mediated immune responses. Granzyme K (GMZK), also designated granzyme-3 or NK-tryptase-2 (NK-TRYP-2), contains one peptidase S1 domain. Granzyme K is a serine protease localizing to the granules of natural killer cells and cytotoxic T lymphocytes. It is primarily expressed in thymus, lung, spleen and peripheral blood leukocytes.
Catalogue number: BS2413P
Applications: Block/Neutralize/Inhibit
Swiss prot: P49863
Form: 1 mg/ml in DI water.
Purity: Synthetic peptide Granzyme K (H85). (Note: the amino acid sequence is proprietary). The purity is > 98%.
Storage temp: Store at 4 degree C short term. Aliquot and store at -20 degree C long term. Avoid freeze-thaw cycles.
Alternative names: EC 3.4.21.-; Granzyme-3; NK-tryptase-2; NK-TRYP-2; Fragmentin-3; GZMK; TRYP2
Additional info: This peptide can be used with studies using BS2413 Granzyme K (H85) pAb.

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