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HAT1 (S361) Peptide

HAT1 (S361) Peptide

Cat no: BS1650P

Supplier: Bioworld Technology, Inc.
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In the intact cell, DNA closely associates with histones and other nuclear proteins to form chromatin. The remodeling of chromatin is believed to be a critical component of transcriptional regulation and a major source of this remodeling is brought about by the acetylation of nucleosomal histones. Acetylation of lysine residues in the amino terminal tail domain of histone results in an allosteric change in the nucleosomal conformation and an increased accessibility to transcription factors by DNA. Conversely, the deacetylation of histones is associated with transcriptional silencing. Several mammalian proteins have been identified as nuclear histone acetylases, including GCN5, PCAF (p300/CBPassociated factor), p300/CBP, HAT1, and the TFIID subunit TAF II p250.
Catalogue number: BS1650P
Applications: Block/Neutralize/Inhibit
Swiss prot: O14929
Form: 1 mg/ml in DI water.
Purity: Synthetic peptide HAT1 (S361). (Note: the amino acid sequence is proprietary). The purity is > 98%.
Storage temp: Store at 4 degree C short term. Aliquot and store at -20 degree C long term. Avoid freeze-thaw cycles.
Alternative names: HAT1; EC 2.3.1.48; HAT1; 8520; HAT1; 603053; O14929;
Additional info: This peptide can be used with studies using BS1650 HAT1 (S361) pAb.

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