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HCN2 (E521) Peptide

Cat no: BS3372P

HCN2 (E521) Peptide

Hyperpolarization-activated, cyclic nucleotide-binding channels (HCN) are voltage-gated cation channels that are activated by direct binding of intracellular cyclic nucleotides. The HCN family consists of four members (HCN1-4), each with a core transmembrane segment domain and a carboxy-terminal 120 amino-acid cyclic nucleotide-binding domain motif. HCN channels are expressed in the brain, heart, thalamus and testis. The pacemaker properties of HCN channels contribute to spontaneous rhythmic activity in the brain and heart. The genes encoding human HCN1 and HCN2 map to chromosomes 5 and 19p13.3, respectively. The genes encoding HCN3 and HCN4 map to chromosomes 1q21.3 and 15q24-q25, respectively.

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SPECIFICATIONS

Catalog Number

BS3372P

Applications

BNI

Form

1 mg/ml in DI water.

Purity

Synthetic peptide HCN2 (E521). (Note: the amino acid sequence is proprietary). The purity is > 98%.

Swiss Prot

Q9UL51

Storage Temp

Store at 4 degree C short term. Aliquot and store at -20 degree C long term. Avoid freeze-thaw cycles.

Additional Info

This peptide can be used with studies using BS3372 HCN2 (E521) pAb.

Alternative Names

HCN2; BCNG-2; BCNG2; HAC-1

SUPPLIER INFO

Bioworld Technology, Inc.

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