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HDAC3 mAb

HDAC3 mAb

Cat no: MB0035


Supplier: Bioworld Technology, Inc.
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Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4), and some other non-histone substrates. Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. Probably participates in the regulation of transcription through its binding to the zinc-finger transcription factor YY1; increases YY1 repression activity. Required to repress transcription of the POU1F1 transcription factor. Acts as a molecular chaperone for shuttling phosphorylated NR2C1 to PML bodies for sumoylation
Catalogue number: MB0035
Reactivities: Human, Mouse, Rat
Hosts: Mouse
Applications: Western Blot
Size: 100ug/100ul
Swiss prot: O15379
Dilutions: WB: 1:1000
Form: liquid
Storage buffer: 1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2.
Concentration: 1ug/ul
Antigen: Recombinant full length Human HDAC3.
Species: This antibody detects endogenous levels of HDAC3 and does not cross-react with related proteins
Molecular weight: Predicted band size:49KDa Observed band size:49KDa
Purity: The antibody was affinity-purified from mouse ascites by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage temp: Store at 4 degrees C short term. Aliquot and store at -20 degrees C long term. Avoid freeze-thaw cycles.
Alternative names: HDAC3; HD3; RPD3-2; SMAP45; HDAC3; 8841; HDAC3; 605166; O15379; HD3; RPD3; RPD3-2;
Additional info: For research use only, not for use in diagnostic procedure.

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