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Heat Shock Protein beta-3, Recombinant, Human, aa1-150, His-tag (HSPB3, Heat Shock 17kD Protein, HSP 17, Protein 3, HSP27, HSPL27)

Cat no: 029661

Heat Shock Protein beta-3, Recombinant, Human, aa1-150, His-tag (HSPB3, Heat Shock 17kD Protein, HSP 17, Protein 3, HSP27, HSPL27)

HSPB3, is a muscle-specific small heat shock protein. It is expressed preferentially in heart and skeletal muscle. Mammalian small heat shock proteins (sHSP) is a abundantly expressed proteins with diverse functions, including the assembly and sequestering of multi-protein complexes, transportation of nascent polypeptide chains across cellular membranes and regulation of protein folding. HSPB3 functions as an ATP-dependent chaperone protein that plays a role in the refolding of denatured proteins and may also Inhibitor of actin polymerization.\n\nSource:\nRecombinant corresponding to aa1-150 from human HSPB3, fused to His-Tag, expressed in E.coli.\n\nAA Sequence:\nMGSSHHHHHH SSGLVPRGSH MAKIILRHLI EIPVRYQEEF EARGLEDCRL DHALYALPGP TIVDLRKTRA AQSPPVDSAA ETPPREGKSH FQILLDVVQF LPEDIIIQTF EGWLLIKAQH GTRMDEHGFI SRSFTRQYKL PDGVEIKDLS AVLCHDGILV VEVKDPVGTK\n\nMolecular Weight:\n~19.1kD\n\nStorage and Stability:\nMay be stored at 4 degrees C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.

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SPECIFICATIONS

Catalog Number

029661

Size

100ug

Form

Supplied as a liquid in 20mM Tris-HCl buffer, pH 8.0, 5% glycerol, 1M urea.

Purity

~85% (SDS-PAGE)

References

1. Fontaine JM., et al. (2005) Biochem Biophys Res Commun. 337(3):1006-11. 2. Suqiyama Y., et al. (2000) J Biol Chem. 275(2):1095-104.

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