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Heme Oxygenase 2, Recombinant, Human (HO-2, HMOX2)

Cat no: H1847-82B

Heme Oxygenase 2, Recombinant, Human (HO-2, HMOX2)

HMOX2 is microsomal enzyme that cleave heme ring at the alpha methane bridge to produce the antioxidant biliverdin, inorganic iron and carbon monoxide. Biliverdin is subsequently converted to bilirubin by bilibverdin reductase. This protein appears to be constitutively expressed in mammalian tissues. HMOX2 is involved in the production of carbon monoxide (CO) in brain, where CO is thought to act as a neurotransmitter. \n\nRecombinant HMOX2 protein was expressed in E.coli and purified by using conventional chromatography techniques.\n\nApplications: \nSuitable for use in Western Blot. Other applications not tested.\n\nRecommended Dilution:\nOptimal dilutions to be determined by the researcher.\n\nEndotoxin: (same/less than)1EU/1ug (LAL).\n\nAmino Acid Sequence:\nMSAEVETSEG VDESEKKNSG ALEKENQMRM ADLSELLKEG TKEAHDRAEN TQFVKDFLKG NIKKELFKLA TTALYFTYSA LEEEMERNKD HPAFAPLYFP MELHRKEALT KDMEYFFGEN WEEQVQCPKA AQKYVERIHY IGQNEPELLV AHAYTRYMGD LSGGQVLKKV AQRALKLPST GEGTQFYLFE NVDNAQQFKQ LYRARMNALD LNMKTKERIV EEANKAFEYN MQIFNELDQA GSTLARETLE DGFPVHDGKG DMRK\n\nMolecular Weight: 30.5kD (264aa)\n\nStorage and Stability:\nMay be stored at 4 degrees C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. Aliquots are stable for at least 6 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

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SPECIFICATIONS

Catalog Number

H1847-82B

Size

100ug

Applications

WB

Form

Supplied as a liquid in 20mM Tris buffer, pH 8.0, 10% glycerol,1mM DTT.

Purity

~90% by SDS-PAGE.

References

Baranano DE., et al. (2001) Proc Natl Acad Sci U S A. 98(20):10996-1002. Dore S., et al. (2002) Free Radic Biol Med. 32(12):1276-82.

Alternative Names

HO-2

Read more on Supplier website

Applications

ELISA

Reactivities

Hum

More info

Applications

IF

Hosts

Mouse

More info

Applications

ELISA, WB

Hosts

Mouse

Reactivities

Hum

More info

Applications

ELISA, FC, WB

Hosts

Mouse

Reactivities

Hum

More info

Applications

ELISA, FC, IHC, WB

Hosts

Mouse

More info

Applications

IHC, WB

Hosts

Rabbit

Reactivities

Hum

More info

Applications

ELISA, WB

Hosts

Rabbit

Reactivities

Hum

More info
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