HESR1 (Hairy/enhancer-of-aplit related with YRPW motif protein 1, Hairy-related transcription factor 1, jHRT1, Cardiovascular helix-loop-helix factor 2, CHF-2, HES-related repressor protein 1, HEY1, CHF2, HERP2, HESR1, HRT1)

HESR-1 belongs to the hairy and enhancer of split-related (HESR) family of basic helix-loop-helix (bHLH)-type transcriptional repressors. It is a downstream effector of Notch signaling which may be required for cardiovascular development. It binds preferentially to the canonical E box sequence 5\\'-CACGTG-3\\'. It represses transcription by the the cardiac transcriptional activators GATA4 and GATA6. HESR1 is expressed in the somitic mesoderm, the central nervous system, the kidney, the heart, nasal epithelium, and limbs. \n\nApplications:\nSuitable for use in ELISA and Western Blot. Other applications not tested.\n\nRecommended Dilution:\nOptimal dilutions to be determined by the researcher.\n\nStorage and Stability:\nLyophilized powder may be stored at -20 degrees C. Stable for 12 months at -20 degrees C. Reconstitute with sterile 40-50% glycerol, ddH2O. Reconstituted product is stable for 12 months at -20 degrees C. Aliquot and store at -20 degrees C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.

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SPECIFICATIONS

Catalog Number

H1560-01A

Size

100ug

Applications

ELISA, WB

Hosts

Mouse

Reactivities

Hum

Form

Supplied as a lyophilized powder in PBS, pH 7.2. Reconstitute with 100ul sterile ddH2O.

P Type

Mab

Purity

Purified by affinity chromatography.

Isotype

IgG

Additional Info

Recognizes human HESR1.

Alternative Names

Hairy/enhancer-of-aplit related with YRPW motif protein 1, Hairy and enhancer of split-related protein 1, Hairy-related transcription factor 1, jHRT1, Cardiovascular helix-loop-helix factor 2, CHF-2, HES-related repressor protein 1, GENE NAMEs: HEY1, CHF2, HERP2, HESR1, HRT1