HIF-3alpha (E354) Peptide

Cat no: BS3483P

Supplier: Bioworld Technology, Inc.

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Cell growth and viability is compromised by oxygen deprivation (hypoxia). Hypoxia-inducible factors, including HIF-1alpha, HIF-1beta (also designated Arnt 1), EPAS-1 (also designated HIF-2alpha) and HIF-3alpha, induce glycolysis, erythropoiesis and angiogenesis in order to restore oxygen homeostasis. Hypoxia-inducible factors are members of the Per-Arnt-Sim (PAS) domain transcription factor family. In response to hypoxia, HIF-1alpha is upregulated and forms a heterodimer with Arnt 1 to form the HIF-1 complex. The HIF-1 complex recognizes and binds to the hypoxia responsive element (HRE) of hypoxia-inducible genes, thereby activating transcription.

Catalogue number:	BS3483P
Applications:	Block/Neutralize/Inhibit
Swiss prot:	Q66K72
Form:	1 mg/ml in DI water.
Purity:	Synthetic peptide HIF-3alpha (E354). (Note: the amino acid sequence is proprietary). The purity is > 98%.
Storage temp:	Store at 4 degree C short term. Aliquot and store at -20 degree C long term. Avoid freeze-thaw cycles.
Alternative names:	Hypoxia-inducible factor 3-alpha; HIF-3-alpha; HIF3-alpha; Basic-helix-loop-helix-PAS protein MOP7; Class E basic helix-loop-helix protein 17; bHLHe17; HIF3-alpha-1; Inhibitory PAS domain protein; IPAS; Member of PAS protein 7; PAS domain-containing protein 7; BHLHE17; MOP7; PASD7; HIF3A
Additional info:	This peptide can be used with studies using BS3483 HIF-3alpha (E354) pAb.

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HIF-3alpha (E354) Peptide

Cat no: BS3483P

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