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Histamine H1 Receptor (K179) pAb

Histamine H1 Receptor (K179) pAb

Cat no: BS2733

Supplier: Bioworld Technology, Inc.
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Histamine is an inflammatory mediator that is ubiquitously expressed and has a broad range of pharmacologic effects. Specifically, it plays a role in the central nervous, gastrointestinal, respiratory and immune systems. The effects of histamine are mediated by a family of G protein-coupled receptors, the Histamine H1, H2, H3 and H4 Receptors. The gene encoding the human Histamine H1 Receptor maps to chromosome 3p25 and is expressed in highest abundance in placenta, with lower levels in lung, skeletal muscle, kidney and brain. The murine Histamine H2 Receptor gene maps to chromosome 13 and is highly expressed in stomach with moderate expression in brain and heart. The gene encoding the human Histamine H3 Receptor is located on chromosome 20 and is expressed as six alternative splice variants in thalamus. The human Histamine H4 Receptor gene maps to chromosome 18q11 and is expressed most abundantly in bone marrow and spleen in addition to peripheral blood leukocytes, thymus, small intestine and colon.
Catalogue number: BS2733
Reactivities: Human
Hosts: Rabbit
Applications: Immunofluorescence, Western Blot
Size: 100ug/100ul
Swiss prot: P35367
Dilutions: WB: 1:500~1:1000 IF: 1:50~1:200
Form: liquid
Storage buffer: 1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2.
Concentration: 1ug/ul
Antigen: Synthetic peptide, corresponding to amino acids 150-200 of Human Histamine H1 Receptor.
Species: Histamine H1 Receptor (K179) pAb detects endogenous levels of Histamine H1 Receptor protein.
Molecular weight: ~ 60 kDa
Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage temp: Store at 4 degrees C short term. Aliquot and store at -20 degrees C long term. Avoid freeze-thaw cycles.
Alternative names: Histamine H1 receptor; H1R; HH1R; HRH1
Additional info: For research use only, not for use in diagnostic procedure.

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