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Histamine H3 Receptor (P326) Peptide

Cat no: BS2627P

Histamine H3 Receptor (P326) Peptide

Histamine is an inflammatory mediator that is ubiquitously expressed and has a broad range of pharmacologic effects. Specifically, it plays a role in the central nervous, gastrointestinal, respiratory and immune systems. The effects of histamine are mediated by a family of G protein-coupled receptors,the Histamine H1, H2, H3 and H4 Receptors. The gene encoding the human Histamine H3 Receptor is located on chromosome 20 and is expressed as six alternative splice variants in thalamus. These isoforms contain either a deletion in the second transmembrane domain or a variable deletion in the third intracellular loop. The existence of multiple H3 Receptor isoforms suggests that H3-mediated effects may be regulated through alternative splicing mechanisms.The H3 Receptor acts as an autoreceptor in the central nervous system (CNS) and modulates histamine synthesis and release.

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SPECIFICATIONS

Catalog Number

BS2627P

Applications

BNI

Form

1 mg/ml in DI water.

Purity

Synthetic peptide Histamine H3 Receptor (P326). (Note: the amino acid sequence is proprietary). The purity is > 98%.

Swiss Prot

Q9Y5N1

Storage Temp

Store at 4 degree C short term. Aliquot and store at -20 degree C long term. Avoid freeze-thaw cycles.

Additional Info

This peptide can be used with studies using BS2627 Histamine H3 Receptor (P326) pAb.

Alternative Names

HH3R; G-protein coupled receptor 97; HRH3; GPCR97; HH3R

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