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Histone H1.0 (R94) pAb

Histone H1.0 (R94) pAb

Cat no: BS1916

Supplier: Bioworld Technology, Inc.
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Histone H10 (H1 histone family, member 0) is a lysine rich member of the H1 family of linker histones. The H1 family of proteins interacts with linker DNA between nucleosomes and mediates compaction into higher order chromatin. Histone H10 is a unique variant considered a replacement linker histone which is expressed and incorporated into chromatin in the absence of DNA replication. In contrast, the majority of somatic H1 histones are replication dependent variants found in proliferating cells. Histone H10 is expressed in cells that are in the terminal stages of differentiation or that have low rates of cell division. Unlike other differentiation-specific linker histones which demonstrate tissue and species-specific expression, Histone H10 is widely expressed in many tissues in most vertebrates.
Catalogue number: BS1916
Reactivities: Human
Hosts: Rabbit
Applications: Immunohistochemistry, Western Blot
Size: 100ug/100ul
Swiss prot: P07305
Dilutions: WB: 1:500~1:1000 IHC: 1:50~1:200
Form: liquid
Storage buffer: 1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2.
Concentration: 1ug/ul
Antigen: Synthetic peptide, corresponding to amino acids 61-110 of Human Histone H1.0.
Species: Histone H1.0 (R94) pAb detects endogenous levels of Histone H1.0 protein.
Molecular weight: ~ 20 kDa
Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage temp: Store at 4 degrees C short term. Aliquot and store at -20 degrees C long term. Avoid freeze-thaw cycles.
Alternative names: H1 0 histone; H1 histone family member 0; H1(0); H1f0; H1F0 protein; Histone H1.0;
Additional info: For research use only, not for use in diagnostic procedure.

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