Histone H2B (K5) Peptide

Eukaryotic histones are basic and water soluble nuclear proteins that form hetero-octameric nucleosome particles by wrapping 146 base pairs of DNA in a left-handed super-helical turn sequentially to form chromosomal fiber. Two molecules of each of the four core histones (H2A, H2B, H3 and H4) form the octamer, which consists of two H2A-H2B dimers and two H3-H4 dimers, forming two nearly symmetrical halves by tertiary structure. Over 80% of nucleosomes contain the linker Histone H1, derived from an intronless gene that interacts with linker DNA between nucleosomes and mediates compaction into higher order chromatin. Histones are subject to posttranslational modification by enzymes primarily on their N-terminal tails, but also in their globular domains. Such modifications include methylation, citrullination, acetylation, phosphorylation, sumoylation, ubiquitination and ADP-ribosylation.

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SPECIFICATIONS

Catalog Number

BS1657P

Applications

BNI

Form

1 mg/ml in DI water.

Purity

Synthetic peptide Histone H2B (K5). (Note: the amino acid sequence is proprietary). The purity is > 98%.

Swiss Prot

P57053

Storage Temp

Store at 4 degree C short term. Aliquot and store at -20 degree C long term. Avoid freeze-thaw cycles.

Additional Info

This peptide can be used with studies using BS1657 Histone H2B (K5) pAb.

Alternative Names

Rabbit anti Histone H2B; H2B.a/g/h/k/l; H2B.1 A; H2B/a; H2B/g; H2B/h; H2B/k; H2B/l; HIST1H2BC; H2BFL; HIST1H2BE; H2BFH; HIST1H2BF; H2BFG; HIST1H2BG; H2BFA; HIST1H2BI; H2BFK