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  Histone H3 (aDi-Methyl R17) pAb

Histone H3 (aDi-Methyl R17) pAb

Cat no: BS7247


Supplier: Bioworld Technology, Inc.
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Modulation of chromatin structure plays an important role in the regulation of transcription in eukaryotes. The nucleosome, made up of DNA wound around eight core histone proteins (two each of H2A, H2B, H3, and H4), is the primary building block of chromatin. The amino-terminal tails of core histones undergo various post-translational modifications, including acetylation, phosphorylation, methylation, and ubiquitination. These modifications occur in response to various stimuli and have a direct effect on the accessibility of chromatin to transcription factors and, therefore, gene expression.
Catalogue number: BS7247
Reactivities: Human, Mouse, Rat
Hosts: Rabbit
Applications: Immunofluorescence, Immunohistochemistry, Immunoprecipitation, Western Blot
Size: 100ug/100ul
Swiss prot: P68431
Dilutions: WB: 1:500~1:2000 IHC: 1:50~1:200 IF: 1:50~1:200 IP: 1:50~1:200 ChIP: 1:50~1:200
Form: liquid
Storage buffer: 1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2.
Concentration: 1ug/ul
Antigen: Synthetic peptide conjugated to KLH derived from within residues 1-100 of Human Histone H3, aDi-methylated at R17.
Species: Histone H3 (aDi-Methyl R17) pAb detects endogenous levels of histone H3 only when asymmetric Di-Methyl at Arg17.
Molecular weight: ~ 17 kDa
Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage temp: Store at 4 degrees C short term. Aliquot and store at -20 degrees C long term. Avoid freeze-thaw cycles.
Alternative names: H3R17me2a; H3R17me2
Additional info: For research use only, not for use in diagnostic procedure.

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