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HIV-1, Recombinant, CT, gp120, gp41 (Human Immunodeficiency Virus-1)

Cat no: H6005-50A

HIV-1, Recombinant, CT, gp120, gp41 (Human Immunodeficiency Virus-1)

gp41/120 is the major HIV protein associated with the HIV envelope. It functions as the viral antireceptor or attachment protein. gp41 (or TM) traverses the envelope, whereas gp120 is present on the outer surface and is noncovalently attached to gp41. The precursor of gp120/41 (gp160) is synthesized in the endoplasmic reticulum and is transported via the golgi body to the cell surface. Upon activation of the envelope glycoprotein (gp120/41) by cellular receptors, gp41 undergoes conformational changes that mediate fusion of the viral and cellular membranes.\n\nSource:\nE. coli\n\nApplications: \nSuitable for use in ELISA. Other applications not tested.\n\nRecommended Dilution:\nOptimal dilutions to be determined by the researcher.\n\nStorage and Stability:\nStore at -20 degrees C. Stable for at least 12 months at -20 degrees C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.

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SPECIFICATIONS

Catalog Number

H6005-50A

Size

1mg

Applications

ELISA

Reactivities

Hum

Form

Supplied as a liquid in 8M urea, 20mM Tris-HCI, 1mM EDTA, 10mM b-mercaptoethanol, pH 8.0.

Purity

S-Sepharose, Ceramic Hydroxyapatite affinity purified. (same/more than) 95% pure as determined by 10% PAGE (coomassie staining).

Additional Info

The protein contains the C-terminus of gp120 and most of gp41.

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