HLA-DOalpha (V111) Peptide

Cat no: BS3134P

Supplier: Bioworld Technology, Inc.

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Reacts with HLA-DO, a heterodimer formed by DNalpha and DObeta subunits in B cells. DNalpha and DObeta are the products of the non-classical class II genes, HLA-DNA and HLA-DOB, respectively. DO forms tight complexes with DM in the endoplasmic reticulum and is thereby sorted to lysosomal vesicles during antigen processing and presentation. It is tightly associated with DM and it is selectively expressed on antigen-presenting cells, such as B cells, dendritic cells and thymic epithelial cells. DO can enhance the efficiency of peptide loading and has been found to stabilize DM at low pH, preserving its chaperon activity. DO-DM complexes are more efficient than DM in protecting empty DR molecules. Reports describe DO as a co-chaperone of DM. This antibody has also been reported to be suitable for western blot and immunoprecipitation.

Catalogue number:	BS3134P
Applications:	Block/Neutralize/Inhibit
Swiss prot:	P06340
Form:	1 mg/ml in DI water.
Purity:	Synthetic peptide HLA-DOalpha (V111). (Note: the amino acid sequence is proprietary). The purity is > 98%.
Storage temp:	Store at 4 degree C short term. Aliquot and store at -20 degree C long term. Avoid freeze-thaw cycles.
Alternative names:	HLA class II histocompatibility antigen; DO alpha chain; MHC DN-alpha; MHC DZ alpha; MHC class II antigen DOA; HLA-DNA; HLA-DZA; HLA-DOA
Additional info:	This peptide can be used with studies using BS3134 HLA-DOalpha (V111) pAb.

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HLA-DOalpha (V111) Peptide

Cat no: BS3134P

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