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HMGB1 (A164) Peptide

HMGB1 (A164) Peptide

Cat no: BS1918P

Supplier: Bioworld Technology, Inc.
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High mobility group (HMG) proteins 1 and 2 are ubiquitous non-histone components of chromatin. Research suggests that the binding of HMG proteins to DNA induces alterations in the DNA architecture, including DNA bending and unwinding of the helix. HMG proteins synergize with Oct-2, ATF-2, c-Jun and members of the NFkB family to activate transcription. Additional studies indicate that phosphorylation of HMG protein is required to stimulate the transcriptional activity of the protein. Human HMG-1 and HMG-2 each contain two DNA-binding domains, termed HMG boxes. HMG proteins bind singlestranded DNA but induce conformational changes in double-stranded DNA alone.
Catalogue number: BS1918P
Applications: Block/Neutralize/Inhibit
Swiss prot: P09429
Form: 1 mg/ml in DI water.
Purity: Synthetic peptide HMGB1 (A164). (Note: the amino acid sequence is proprietary). The purity is > 98%.
Storage temp: Store at 4 degree C short term. Aliquot and store at -20 degree C long term. Avoid freeze-thaw cycles.
Alternative names: High mobility group protein B1; High mobility group protein 1; HMG-1; HMGB1; HMG1
Additional info: This peptide can be used with studies using BS1918 HMGB1 (A164) pAb.

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