HMGB2 (K165) Peptide

Cat no: BS1967P

Supplier: Bioworld Technology, Inc.

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High mobility group (HMG) proteins 1 and 2 are ubiquitous non-histone components of chromatin. Evidence suggests that the binding of HMG proteins to DNA induces alterations in the DNA architecture including DNA bending and unwinding of the helix. HMG proteins synergize with Oct-2, members of the N kB family, ATF-2 and c-Jun to activate transcription. Other studies indicate that phosphorylation of HMG protein is required to stimulate the transcriptional activity of the protein. Human HMG-1 and HMG-2 both contain two DNA-binding domains, termed HMG boxes. HMG proteins bind single-stranded DNA but induce conformational changes in double-stranded DNA alone.

Catalogue number:	BS1967P
Applications:	Block/Neutralize/Inhibit
Swiss prot:	P26583
Form:	1 mg/ml in DI water.
Purity:	Synthetic peptide HMGB2 (K165). (Note: the amino acid sequence is proprietary). The purity is > 98%.
Storage temp:	Store at 4 degree C short term. Aliquot and store at -20 degree C long term. Avoid freeze-thaw cycles.
Alternative names:	High mobility group (nonhistone chromosomal) protein 2; high mobility group box 2; High mobility group protein 2; High mobility group protein B2; high-mobility group (nonhistone chromosomal) protein 2; HMG 2; HMG B2; HMG-B2; HMG-2; HMG2; HMGB-2;
Additional info:	This peptide can be used with studies using BS1967 HMGB2 (K165) pAb.

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HMGB2 (K165) Peptide

Cat no: BS1967P

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