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Hox-B9 (R237) Peptide

Hox-B9 (R237) Peptide

Cat no: BS1940P


Supplier: Bioworld Technology, Inc.
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The Hox proteins play a role in development and cellular differentiation by regulating downstream target genes. Specifically, the Hox proteins direct DNA-protein and protein-protein interactions that assist in determining the morphologic features associated with the anterior-posterior body axis. Themammalian Hox gene complex consists of 39 genes that are located on four linkage groups, which are dispersed over four chromosomes. Hox genes that occupy the same relative position along the 5' to 3' coordinate (trans-paralogous genes) are more similar in sequence and expression pattern than adjacent Hox genes on the same chromosome. In mice, the HoxB cluster contains HoxB1 to HoxB9 and HoxB13, which are transcribed in the same direction. HoxB9 associates with the transcriptional cofactors BTG1 and BTG2, which enhance HoxB9 ranscription. Alterations in HoxB9 expression, as with other Hox family member, has been implicated in leukemia.
Catalogue number: BS1940P
Applications: Block/Neutralize/Inhibit
Swiss prot: P17482
Form: 1 mg/ml in DI water.
Purity: Synthetic peptide Hox-B9 (R237). (Note: the amino acid sequence is proprietary). The purity is > 98%.
Storage temp: Store at 4 degree C short term. Aliquot and store at -20 degree C long term. Avoid freeze-thaw cycles.
Alternative names: Hox-2E; Hox-2.5; HOXB9; HOX2E
Additional info: This peptide can be used with studies using BS1940 Hox-B9 (R237) pAb.

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