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HPK1 (L397) Peptide

HPK1 (L397) Peptide

Cat no: BS2115P

Supplier: Bioworld Technology, Inc.
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Several mammalian kinases have been identified with sequence similarity to the Saccharomyces cerevisiae serine/threonine kinase STE20. STE20 is involved in relaying signals from G protein coupled receptors to cytosolic MAP kinase cascades, and it lies upstream of a MAP kinase kinase kinase. Mammalian STE20-like kinases include HPK1, KHS, GLK, NIK, YSK1, Krs-1, Krs-2 and GC kinase. HPK1 (hematopoietic progenitor kinase 1), like many other STE20-like kinases, specifically activates the JNK signaling pathway. HPK1 binds to and phosphorylates MEKK, suggesting it plays an important role in regulating the stress responsive JNK/SAPK signaling pathway.
Catalogue number: BS2115P
Applications: Block/Neutralize/Inhibit
Swiss prot: Q92918
Form: 1 mg/ml in DI water.
Purity: Synthetic peptide HPK1 (L397). (Note: the amino acid sequence is proprietary). The purity is > 98%.
Storage temp: Store at 4 degree C short term. Aliquot and store at -20 degree C long term. Avoid freeze-thaw cycles.
Alternative names: Mitogen-activated protein kinase kinase kinase kinase 1; MAPK/ERK kinase kinase kinase 1; MEK kinase kinase 1; MEKKK 1; Hematopoietic progenitor kinase
Additional info: This peptide can be used with studies using BS2115 HPK1 (L397) pAb.

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