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HRF (K100) Peptide

Cat no: BS1928P

HRF (K100) Peptide

Histamine is an inflammatory mediator that is ubiquitously expressed and has a broad range of pharmacologic effects. Specifically, it plays a role in the central nervous, gastrointestinal, respiratory and immune systems. Histamine release is mediated by the stimulation of mast cells and basophils. Histamine-releasing factor (HRF) is a cytokine-like molecule that causes the release of histamine, IL-4 and IL-13 from basophils as well as the secretion of IL-8 and a calcium response in eosinophils. HRF belongs to the translationally controlled tumor protein (TCTP) family and is detected as a protein of 21 kDa in mice and 23 kDa in human. It is expressed in several healthy and tumoral cells, including erythrocytes, hepatocytes, macrophages, platelets, keratinocytes, erythroleukemia cells, gliomas, melanomas, hepatoblastomas and lymphomas, and it is localized in the cytoplasm. HRF plays a pivotal role in allergic diseases, and due to its wide distribution in brain, is thought to be involved in neurodegenerative disorders, such as Alzheimer

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SPECIFICATIONS

Catalog Number

BS1928P

Applications

BNI

Form

1 mg/ml in DI water.

Purity

Synthetic peptide HRF (K100). (Note: the amino acid sequence is proprietary). The purity is > 98%.

Swiss Prot

P13693

Storage Temp

Store at 4 degree C short term. Aliquot and store at -20 degree C long term. Avoid freeze-thaw cycles.

Additional Info

This peptide can be used with studies using BS1928 HRF (K100) pAb.

Alternative Names

TPT1; TCTP; TPT1; Histamine-releasing factor; Fortilin; Translationally-controlled tumor protein; p23

SUPPLIER INFO

Bioworld Technology, Inc.

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