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HRF (K100) Peptide

HRF (K100) Peptide

Cat no: BS1928P


Supplier: Bioworld Technology, Inc.
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Histamine is an inflammatory mediator that is ubiquitously expressed and has a broad range of pharmacologic effects. Specifically, it plays a role in the central nervous, gastrointestinal, respiratory and immune systems. Histamine release is mediated by the stimulation of mast cells and basophils. Histamine-releasing factor (HRF) is a cytokine-like molecule that causes the release of histamine, IL-4 and IL-13 from basophils as well as the secretion of IL-8 and a calcium response in eosinophils. HRF belongs to the translationally controlled tumor protein (TCTP) family and is detected as a protein of 21 kDa in mice and 23 kDa in human. It is expressed in several healthy and tumoral cells, including erythrocytes, hepatocytes, macrophages, platelets, keratinocytes, erythroleukemia cells, gliomas, melanomas, hepatoblastomas and lymphomas, and it is localized in the cytoplasm. HRF plays a pivotal role in allergic diseases, and due to its wide distribution in brain, is thought to be involved in neurodegenerative disorders, such as Alzheimer
Catalogue number: BS1928P
Applications: Block/Neutralize/Inhibit
Swiss prot: P13693
Form: 1 mg/ml in DI water.
Purity: Synthetic peptide HRF (K100). (Note: the amino acid sequence is proprietary). The purity is > 98%.
Storage temp: Store at 4 degree C short term. Aliquot and store at -20 degree C long term. Avoid freeze-thaw cycles.
Alternative names: TPT1; TCTP; TPT1; Histamine-releasing factor; Fortilin; Translationally-controlled tumor protein; p23
Additional info: This peptide can be used with studies using BS1928 HRF (K100) pAb.

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