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HSF2 (R432) Peptide

HSF2 (R432) Peptide

Cat no: BS2033P

Supplier: Bioworld Technology, Inc.
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Prokaryotic and eukaryotic cells respond to thermal and chemical stress by inducing a group of genes collectively designated heat shock genes. In eukaryotes, this gene expression is regulated primarily at the transcription level. Heat shock transcription factors (HSF, also designated HSTF) 1 and 2 are involved in this regulation. HSF1 and HSF2 are upregulated by estrogen at both the mRNA and protein level. HSF1 is normally found as a monomer whose transcriptional activity is repressed by constitutive phosphorylation. Upon activation, HSF1 forms trimers, gains DNA binding activity and is translocated to the nucleus. HSF2 activity is associated with differentiation and development, and, like HSF1, binds DNA as a trimer. Both HSF1 and HSF2 are known to be induced by proteasome inhibitors of the ubiquitin pathway.
Catalogue number: BS2033P
Applications: Block/Neutralize/Inhibit
Swiss prot: Q03933
Form: 1 mg/ml in DI water.
Purity: Synthetic peptide HSF2 (R432). (Note: the amino acid sequence is proprietary). The purity is > 98%.
Storage temp: Store at 4 degree C short term. Aliquot and store at -20 degree C long term. Avoid freeze-thaw cycles.
Alternative names: Heat shock factor protein 2; HSF 2; Heat shock transcription factor 2; HSTF 2; HSTF2
Additional info: This peptide can be used with studies using BS2033 HSF2 (R432) pAb.

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