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HSP27 mAb

HSP27 mAb

Cat no: MB0141


Supplier: Bioworld Technology, Inc.
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Hsp27, also referred to as the Estrogen-Regulated 24K protein and HSP28, is one of several small heat shock proteins (HSP) produced by all organisms studied. Hsp27 synthesis is induced by elevated temperature, as well as estrogen in hormone responsive cells. This protein is involved in stress resistance and actin organization. Interestingly, human HSP27 also shares greater than 50% homology with low molecular weight Drosophila HSP's and mammalian a-crystalline lens protein. Because of the estrogen-responsive nature of Hsp27, this protein has been studied extensively in human estrogen-responsive tissues such as cervix, endometrium and breast tissue. This work has led to the suggestion that Hsp27 may be a useful marker in classifying various hormone sensitive tumors.
Catalogue number: MB0141
Reactivities: Human, Non-Human Primate
Hosts: Mouse
Applications: Western Blot
Size: 100ug/100ul
Swiss prot: P04792
Dilutions: WB: 1:1000 ICC: 1:100~500
Form: liquid
Storage buffer: 1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2.
Concentration: 1ug/ul
Antigen: Recombinant full length Human HSP27.
Species: This antibody detects endogenous levels of HSP27 and does not cross-react with related proteins
Molecular weight: Predicted band size:23KDa Observed band size:27KDa
Purity: The antibody was affinity-purified from mouse ascites by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage temp: Store at 4 degrees C short term. Aliquot and store at -20 degrees C long term. Avoid freeze-thaw cycles.
Alternative names: 28 kDa heat shock protein; Estrogen-regulated 24 kDa protein; Heat shock 27 kDa protein; Stress-responsive protein 27; HSPB1; HspB1; Hsp B1; CMT2F; HMN2B; HSP27; HSP28; Hsp25; SRP27; HS.76067; HSP 27
Additional info: For research use only, not for use in diagnostic procedure.

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