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HSP90B (E222) Peptide

Cat no: BS1851P

HSP90B (E222) Peptide

HSP 90 family members guide the normal folding, intracellular disposition and proteolytic turnover of many key regulators of cell growth, differentiation and survival. HSP 90alpha, also designated HSP90A, HSP 86 and LPS-associated protein 2 (LAP2), is a cytosolic enhancer of inducible nitric-oxide synthase (iNOS), with chaperone activity that is important for the transcriptional activity of p53. HSP 90beta, also designated HSP90B, HSP 84 and HSPC2, is a cytosolic protein that participates in signaling pathways with PKC epsilon to protect cells from external damage, particularly in heat shock-mediated events. GRP 94, also known as tumor rejection antigen 1 (TRA1), ECGP and GP96, localizes to the ER, is highly expressed in BGC-823 human gastric carcinoma cells and is upregulated in human endothelial cells in response to hypoxia by HIF-1.

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SPECIFICATIONS

Catalog Number

BS1851P

Applications

BNI

Form

1 mg/ml in DI water.

Purity

Synthetic peptide HSP90B (E222). (Note: the amino acid sequence is proprietary). The purity is > 98%.

Swiss Prot

P08238

Storage Temp

Store at 4 degree C short term. Aliquot and store at -20 degree C long term. Avoid freeze-thaw cycles.

Additional Info

This peptide can be used with studies using BS1851 HSP90B (E222) pAb.

Alternative Names

HSP90B1; ECGP; GP96; GRP94; TRA1

SUPPLIER INFO

Bioworld Technology, Inc.

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