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HSP90B mAb

HSP90B mAb

Cat no: MB0142


Supplier: Bioworld Technology, Inc.
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HSP 90 family members guide the normal folding, intracellular disposition and proteolytic turnover of many key regulators of cell growth, differentiation and survival. HSP 90alpha, also designated HSP90A, HSP 86 and LPS-associated protein 2 (LAP2), is a cytosolic enhancer of inducible nitric-oxide synthase (iNOS), with chaperone activity that is important for the transcriptional activity of p53. HSP 90beta, also designated HSP90B, HSP 84 and HSPC2, is a cytosolic protein that participates in signaling pathways with PKC epsilon to protect cells from external damage, particularly in heat shock-mediated events. GRP 94, also known as tumor rejection antigen 1 (TRA1), ECGP and GP96, localizes to the ER, is highly expressed in BGC-823 human gastric carcinoma cells and is upregulated in human endothelial cells in response to hypoxia by HIF-1.
Catalogue number: MB0142
Reactivities: Human, Mouse, Rat, Non-Human Primate
Hosts: Mouse
Applications: Western Blot
Size: 100ug/100ul
Swiss prot: P08238
Dilutions: WB: 1:500~1000 ICC: 1:50~200
Form: liquid
Storage buffer: 1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2.
Concentration: 1ug/ul
Antigen: Recombinant full length Human HSP90B.
Species: This antibody detects endogenous levels of HSP90 and does not cross-react with related proteins
Molecular weight: Predicted band size:90KDa Observed band size:90KDa
Purity: The antibody was affinity-purified from mouse ascites by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage temp: Store at 4 degrees C short term. Aliquot and store at -20 degrees C long term. Avoid freeze-thaw cycles.
Alternative names: HSP84; HSPC2; HSPCB; D6S182; HSP90B; heat shock 90kDa protein 1 alpha; Heat shock protein 90kDa alpha cytosolic class A member 1; Heat shock protein 90kDa alpha cytosolic class B member 1; Heat shock protein HSP 90 alpha; Heat shock protein HSP 90 beta; HSP 84; HSP 86; Hsp 90; HSP84; HSP86; Hsp89; Hsp90; HSP90 Beta; HSP90A; HSP90AA1; HSP90AB1; HSP90B; HSP90N; HSPC1; HSPC2; HSPCA; HSPCAL1; HSPCAL4; HSPCB; HSPN; LAP2; Lipopolysaccharide associated protein2; LPS associated protein 2; NY REN 38 antigen.
Additional info: For research use only, not for use in diagnostic procedure.

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