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HXK I / HK1 mAb

HXK I / HK1 mAb

Cat no: MB0140

Supplier: Bioworld Technology, Inc.
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Hexokinases phosphorylate glucose to produce glucose-6-phosphate, the first step in most glucose metabolism pathways. This gene encodes a ubiquitous form of hexokinase which localizes to the outer membrane of mitochondria. Mutations in this gene have been associated with hemolytic anemia due to hexokinase deficiency. Alternative splicing of this gene results in five transcript variants which encode different isoforms, some of which are tissue-specific. Each isoform has a distinct N-terminus; the remainder of the protein is identical among all the isoforms. A sixth transcript variant has been described, but due to the presence of several stop codons, it is not thought to encode a protein.
Catalogue number: MB0140
Reactivities: Human
Hosts: Mouse
Applications: Western Blot
Size: 100ug/100ul
Swiss prot: P19367
Dilutions: WB: 1:1000~10000 ICC: 1:100~500
Form: liquid
Storage buffer: 1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2.
Concentration: 1ug/ul
Antigen: Recombinant full length Human HXK I.
Species: This antibody detects endogenous levels of Hexokinase-1 and does not cross-react with related proteins
Molecular weight: Predicted band size:102kDa Observed band size:102kDa
Purity: The antibody was affinity-purified from mouse ascites by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage temp: Store at 4 degrees C short term. Aliquot and store at -20 degrees C long term. Avoid freeze-thaw cycles.
Alternative names: HK I,glycolytic enzyme,hexokinase type I brain form hexokinase; HKI; HXK1; HK1-ta; HK1-tb; HK1-tc; Hexokinase-1; Hexokinase 1; Hexokinase1
Additional info: For research use only, not for use in diagnostic procedure.

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