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ICAM-1 (Q506) Peptide

Cat no: BS2980P

ICAM-1 (Q506) Peptide

ICAM1 is a 85-110 kDa single chain type 1 integral membrane glycoprotein with an extracellular domain of five immunoglobulin superfamily repeats, a transmembrane region and a cytoplasmic domain. It shares considerable amino acid sequence homology with ICAM3 and with ICAM2. ICAM1 is expressed by activated endothelial cells. It is detected on cells of many other lineages (e.g. epithelial cells, fibroblasts, chondrocytes, B lymphocytes, T lymphocytes (low), monocytes, macrophages, dendritic cells and neutrophils, with lower levels that increase in inflammation. Also, ICAM1 is detected in some carcinoma and melanoma cells. Soluble ICAM1 is detectable in the plasma and is elevated in patients with various inflammatory syndromes. It is the receptor for rhinoviruses and malaria.

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SPECIFICATIONS

Catalog Number

BS2980P

Applications

BNI

Form

1 mg/ml in DI water.

Purity

Synthetic peptide ICAM-1 (Q506). (Note: the amino acid sequence is proprietary). The purity is > 98%.

Swiss Prot

P05362

Storage Temp

Store at 4 degree C short term. Aliquot and store at -20 degree C long term. Avoid freeze-thaw cycles.

Additional Info

This peptide can be used with studies using BS2980 ICAM-1 (Q506) pAb.

Alternative Names

CD54; ICAM-1; Major group rhinovirus receptor; CD54 antigen; ICAM1

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