ICAM-2 Peptide

Cat no: BS5761P

Supplier: Bioworld Technology, Inc.

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Cell adhesion molecules are a family of closely related cell surface glycoproteins involved in cell-cell interactions during growth and are thought to play important, yet separate, roles in embryogenesis and development. The intracellular adhesion molecule-1 (ICAM-1), also referred to as CD54, is an integral membrane protein of the immunoglobulin superfamily and recognizes the b2a1 and b2aM Integrins. ICAM-2 functions as a ligand for lymphocyte function-associated antigen-1 (LFA-1) and is involved in leukocyte adhesion. ICAM-3 is highly expressed on the surface of human eosinophils, and when bound to ligand may inhibit eosinophil inflammatory responses and survival. ICAM-4, also known as LW glycoprotein, interacts with Integrins aLb2, aMb2, a4b1, the aV family and aIIbb3, and selective binding to different integrins may be relevant to the pathology in a number of red blood cell associated diseases. Lastly, ICAM-5, expressed on telencephalic neurons, binds CD11a/CD18 and thus may act as an adhesion molecule for leukocyte binding in the central nervous system.

Catalogue number:	BS5761P
Applications:	Block/Neutralize/Inhibit
Swiss prot:	P13598
Form:	1 mg/ml in DI water.
Purity:	Synthetic peptide ICAM-2. (Note: the amino acid sequence is proprietary). The purity is > 98%.
Storage temp:	Store at 4 degree C short term. Aliquot and store at -20 degree C long term. Avoid freeze-thaw cycles.
Alternative names:	Intercellular adhesion molecule 2; ICAM-2; CD102; ICAM2
Additional info:	This peptide can be used with studies using BS5761 ICAM-2 pAb.

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ICAM-2 Peptide

Cat no: BS5761P

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