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IFI-16 (N772) pAb

IFI-16 (N772) pAb

Cat no: BS3865

Supplier: Bioworld Technology, Inc.
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Interferon-gamma inducible protein 16 (IFI16) belongs to the HIN-200 family of transcriptional regulator linked to cell cycle regulation and differentiation by modulating the activities of multiple transcriptional factors, such as p53 and Rb. The HIN-200 (hematopoeitic interferon-inducible nuclear antigens with 200 amino acid repeat) family members contain a DNA binding domain, a transcriptional regulatory domain, DAPIN/PAAD domain associated with interferon response and a binding domain for BRCA1. IFI16 may have a role in the regulation of hematopoeitic cell differentiation and also be involved in DNA repair since it becomes a component of the DNA repair multi-protein BASC complex after UV-induced DNA damage. IFI16 is strongly induced by gamma interferon in vivo.
Catalogue number: BS3865
Reactivities: Human
Hosts: Rabbit
Applications: Western Blot
Size: 100ug/100ul
Swiss prot: Q16666
Dilutions: WB: 1:500~1:1000
Form: liquid
Storage buffer: 1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2.
Concentration: 1ug/ul
Antigen: Synthetic peptide, corresponding to amino acids 740-795 of Human IFI-16.
Species: IFI-16 (N772) pAb detects endogenous levels of IFI-16 protein.
Molecular weight: ~ 88 kDa
Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage temp: Store at 4 degrees C short term. Aliquot and store at -20 degrees C long term. Avoid freeze-thaw cycles.
Alternative names: Gamma-interferon-inducible protein Ifi-16; Interferon-inducible myeloid differentiation transcriptional activator; IFI16; IFNGIP1
Additional info: For research use only, not for use in diagnostic procedure.

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